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성균관대학교-의과대학-생리학교실-Ion-Channel-Targeted-Therapy-Laboratory-logo

PUBLICATIONS

98

peer-reviewed publications

From Target to Therapeutic
One Ion Channel at a Time.

Our laboratory has targeted ion channels in allergic disease and sensory disorders, with three IND-approved candidates to date.
Every project begins the same way: identify the channel, map the binding site, validate the mechanism, advance the candidate.

3

IND-approved candidates to date

9

patents (Korea/PCT/US)

Selected Publications — High-Impact Work

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CANCER RESEARCH · 2025
IF 16.6 (2024 JCR)
Oncology #16/328

Nutrient Availability Dictates Cancer 
Metabolism-Based Therapeutic Responses 
to Non-oncology Drugs

Pyun WY et al., Nam JH (Co-corresponding)

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BIOMEDICINE & PHARMACOTHERAPY · 2025
IF 7.5 (2024 JCR)
Pharmacology & Pharmacy #19/352

Polypharmacological effects of honokiol 
on allergic rhinitis: Modulation of 
TMEM16A, TRPV1, and calcium signaling

Phan HTL et al., Nam JH (Co-corresponding)

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PNAS · 2024
IF 9.1 (2024 JCR)
Multidisciplinary Sciences #14/135

Distinct modulation of calcium-activated 
chloride channel TMEM16A by a novel 
drug-binding site

Roh JW et al., Nam JH (Co-corresponding)

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PAIN · 2024
IF 5.5 (2024 JCR)
Anesthesiology #6/68

Physiological profiling of cannabidiol 
reveals profound inhibition of 
sensory neurons

Chahyadinata G et al., Nam JH (Co-first)

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EXPERIMENTAL & MOLECULAR MEDICINE · 2023
IF 12.8 (2024 JCR)
Biochemistry & Molecular Biology #14/320

Overlooked KCNQ4 variants augment 
the risk of hearing loss

Oh KS et al., Nam JH (Co-corresponding)

PHYTOMEDICINE · 2023
IF 8.3 (2024 JCR) 
Integrative & Complementary Medicine #1/45

Multi-target modulation of ion channels 
underlying the analgesic effects of 
alpha-mangostin in dorsal root ganglion 
neurons

Kim SE et al., Nam JH (Co-corresponding)

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